Senior Manager, Process Development (Chemistry)
Pleasanton, CA 
Posted 1 month ago
Job Description

About the role:

10x is looking for an outstanding Sr Manager to join the Process Development group and lead a team of chemists in the development and transfer of new chemistries from concept to full implementation in a commercial manufacturing facility. The Process Development team interfaces between early stage R&D and Production is deeply embedded in both organizations. This position works cross-functionally with multiple groups such as Chemistry, Microfluidics, Molecular Biology, Engineering, QC, Production, and Supply Chain. Candidates must have a broad working knowledge of organic chemistries related to polymers, oligonucleotides, surface chemistries and be able to independently and creatively translate those principles to establish production processes at commercial scale in a full Production facility. This is a lead from the bench role. The successful applicant will have exceptional attention to detail and the ability to meticulously execute and analyze highly complex experiments. Previous industry experience successfully commercializing and supporting similar processes is essential.

Individuals applying for this position must be self-starters, strategic thinkers, action driven, flexible in changing direction and methods, thrive in a fast paced environment, excel at managing multiple priorities, succeed in communicating with all levels within the organization and provide immediate contribution.

What you will be doing:

  • Lead a team responsible for commercializing new chemistries and production processes required to produce 10x reagents and consumables.
  • Build, develop, and lead a team of organic chemists responsible for a broad range of polymer, oligonucleotide, surface, and other NGS related chemistries and associated analytical methods..
  • Guide development plans to ensure robust manufacturing processes through use of FMEA and risk assessment, guardbanding, material selection, and QC strategy.
  • Direct experimentation to develop a first principles understanding of underlying reaction mechanisms and interactions. Drive root cause analysis of novel failure modes, and ensure rapid implementation of appropriate solutions.
  • Scale up and develop alternative production processes to meet demand as 10x Genomics continues to grow.
  • Drive QC strategy through the use of standard analytical methods or development of novel analytical methods to ensure processes are in control.
  • Communicate and present results clearly and contribute data for making critical design decisions through accurate record of experimental details, documentation, and presentations.
  • Sustain and improve on market products for reliability, yield, vendor quality, continuity of supply, and part obsolescence.
  • Drive innovation and continuous improvement in a fast-paced, dynamic environment.

Minimum Requirements:

  • PhD in Organic Chemistry, Polymer Chemistry, Surface Chemistry, Analytical Chemistry, Process Chemistry or related field
  • 8+ years of relevant experience in biotechnology or life science related industry.
  • Proven ability to lead a chemistry related process development team
  • Strong process development experience demonstrating control of manufacturing processes through appropriate Process Design and QC methods.
  • Ability to integrate a broad range of scientific and engineering disciplines.
  • Ability to design meaningful experiments and in depth analysis of results. Experience using statistical tools, such as JMP, is beneficial.
  • Ability to develop, validate and transfer processes to manufacturing or OEM vendors.
  • Excellent collaboration and communication skills.
  • Ability to travel internationally as needed.
  • Desire to be part of a rapidly evolving organization, with a compelling technology, and taking products and processes to the next level.

#LI-MH1 #on-site

Below is the base pay range for this full time position. The actual base pay will depend on several factors unique to each candidate, including one's skills, qualifications, and experience. At 10x, base pay is also just one component of the Company's total compensation package. This role is also eligible for 10x's equity grants, its comprehensive health and retirement benefit programs, and its annual bonus program or sales incentive program. Your 10x recruiter can share more about the Company's total compensation package during the hiring process.

Pay Range
$170,000$230,000 USD

About 10x Genomics

At 10x Genomics, accelerating our understanding of biology is more than a mission for us. It is a commitment. This is the century of biology, and the breakthroughs we make now have the potential to change the world.

We enable scientists to advance their research, allowing them to address scientific questions they did not even know they could ask. Our tools have enabled fundamental discoveries across biology including cancer, immunology, and neuroscience.

Our teams are empowered and encouraged to follow their passions, pursue new ideas, and perform at their best in an inclusive and dynamic environment. We know that behind every scientific breakthrough, there is a deep infrastructure of talented people driving the life sciences industry and making it possible for scientists and clinicians to make new strides. We are dedicated to finding the very best person for every aspect of our work because the innovations and discoveries that we enable together will lead to better technologies, better treatments, and a better future. Find out how you can make a 10x difference.

Individuals seeking employment at 10x Genomics are considered without regards to race, color, religion, national origin, age, sex, marital status, ancestry, physical or mental disability, veteran status, gender identity, or sexual orientation,or any other characteristic protected by applicable law.

10x does not accept unsolicited applicants submitted by third-party recruiters or agencies. Any resume or application submitted to 10x without a vendor agreement in place will be considered unsolicited and property of 10x, and 10x will not pay a placement fee.


Job Summary
Start Date
As soon as possible
Employment Term and Type
Regular, Full Time
Required Education
Required Experience
8+ years
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